SCHEMBL30685756

SCHEMBL30685756

O=C(O)COc1ccc(C2(c3ccc(O)cc3)C(=O)Nc3ccccc32)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.68
ADORA3 P0DMS8 1/20 0.68
KCNH2 Q12809 1/20 0.68
MAPT P10636 3/20 0.58
LMNA P02545 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
XBP1 P17861 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
ALOX15 P16050 1/20 0.45
CYP19A1 P11511 1/20 0.44
ESR1 P03372 1/20 0.44
CNR1 P21554 1/20 0.43
HTT P42858 1/20 0.43
GPR35 Q9HC97 1/20 0.43
GPR55 Q9Y2T6 1/20 0.43
FFAR1 O14842 2/20 0.43
PTPN7 P35236 2/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13145362 0.83 CHRM2 (0.78) CHRM2ADORA3KCNH2MAPTLMNA
SCHEMBL25502467 0.83 CHRM2 (0.82) CHRM2ADORA3KCNH2MAPTLMNA
SCHEMBL30685743 0.83 CHRM2 (0.61) CHRM2ADORA3KCNH2MAPTLMNA
SCHEMBL2716060 0.83 CHRM2 (0.93) CHRM2ADORA3KCNH2MAPTLMNA
Oxyphenisatine SCHEMBL239513 0.83 CHRM2 (1.00) CHRM2ADORA3KCNH2MAPTLMNA
Oxyphenisatine SCHEMBL35387956 0.83 CHRM2 (1.00) CHRM2ADORA3KCNH2MAPTLMNA
SCHEMBL11748640 0.81 CHRM2 (0.78) CHRM2ADORA3KCNH2MAPTLMNA
SCHEMBL3198592 0.81 CHRM2 (0.78) CHRM2ADORA3KCNH2MAPTLMNA
SCHEMBL29176372 0.80 ALOX15 (0.42) CHRM2ADORA3KCNH2MAPTMEN1
SCHEMBL13145367 0.79 CHRM2 (0.80) CHRM2ADORA3KCNH2MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447380-A Hapten and artificial antigen for simultaneously detecting phenolic butanes in weight-losing food and application thereof 华南农业大学 2024-01-26 CN disclosed