Lithium

Lithium

SCHEMBL30686180

CC(C)(C)O[Al](OC(C)(C)C)OC(C)(C)C.[Li]

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL107947 0.96 ALDH1A1 (0.36) ALDH1A1TSHRTDP1
SCHEMBL1939142 0.92 ALDH1A1 (0.33) ALDH1A1TSHRTDP1
SCHEMBL3898656 0.92 ALDH1A1 (0.33) ALDH1A1TSHRTDP1
Hydrochloric Acid SCHEMBL28815855 0.92 ALDH1A1 (0.33) ALDH1A1TSHRTDP1
SCHEMBL590 0.92 ALDH1A1 (0.33) ALDH1A1TSHRTDP1
SCHEMBL3889962 0.92 ALDH1A1 (0.33) ALDH1A1TSHRTDP1
Water SCHEMBL11536125 0.92 ALDH1A1 (0.33) ALDH1A1TSHRTDP1
Lithium Ion SCHEMBL808460 0.88 TSHR (0.31) ALDH1A1TSHRTDP1
SCHEMBL3898653 0.88 TSHR (0.31) ALDH1A1TSHRTDP1
Potassium Ion SCHEMBL3889958 0.88 TSHR (0.31) ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117279933-A Cyclic compounds having selective KRAS inhibition relative to HRAS and NRAS 中外制药株式会社 2023-12-22 CN disclosed