Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 1/20 | 0.50 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.38 |
| ▸ | KDM6B | O15054 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 8/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15770057 | 0.77 | LATS1 (0.55) | LATS1PRKCQCSNK1EHDAC1MAPT | |
| SCHEMBL30686213 | 0.74 | KMT2A (0.55) | PRKCQCSNK1EHDAC1KDM4EMEN1 | |
| SCHEMBL30686207 | 0.74 | PRKCQ (0.42) | LATS1PRKCQCSNK1EHDAC1KDM4E | |
| SCHEMBL30686366 | 0.74 | LATS1 (0.40) | LATS1PRKCQCSNK1EHDAC1MEN1 | |
| SCHEMBL28509680 | 0.74 | KDM4C (0.49) | KDM4CKDM6BKDM4EMEN1KDM4A | |
| SCHEMBL29664704 | 0.73 | KDM4C (0.47) | KDM4CKDM6BKDM4EMEN1KDM4A | |
| SCHEMBL18394720 | 0.73 | KDM4C (0.47) | KDM4CKDM6BKDM4EMEN1KDM4A | |
| SCHEMBL18395417 | 0.71 | SMN1; SMN2 (0.47) | KDM4CKDM6BKDM4EMEN1KDM4A | |
| SCHEMBL29575095 | 0.71 | SMN1; SMN2 (0.47) | KDM4CKDM6BKDM4EMEN1KDM4A | |
| SCHEMBL31368899 | 0.70 | LATS1 (0.39) | LATS1PRKCQCSNK1EHDAC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532496-A1 | NOVEL PAR-2 INHIBITORS | Domain Therapeutics (FR) | 2025-04-09 | — | — | EP | claimed |
| WO-2023233033-A1 | NOVEL PAR-2 INHIBITORS | DOMAIN THERAPEUTICS (FR) | 2023-12-07 | — | — | WO | claimed |