Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | LATS1 | O95835 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 5/20 | 0.35 |
| ▸ | FLT3 | P36888 | 5/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCND2 | P30279 | 1/20 | 0.34 |
| ▸ | CCND3 | P30281 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30686350 | 0.74 | LATS1 (0.50) | PRKCQLATS1HDAC1CSNK1ECDK4 | |
| SCHEMBL31368987 | 0.73 | PRKCQ (0.41) | PRKCQLATS1HDAC1PRKD1PRKD2 | |
| SCHEMBL30686366 | 0.72 | LATS1 (0.40) | PRKCQLATS1HDAC1PRKD1PRKD2 | |
| SCHEMBL30686213 | 0.72 | KMT2A (0.55) | PRKCQHDAC1PRKD1PRKD2MYC | |
| SCHEMBL18096106 | 0.69 | PRKCQ (0.42) | PRKCQLATS1HDAC1PRKD1PRKD2 | |
| SCHEMBL16236124 | 0.68 | ALDH1A1 (0.53) | PRKCQLATS1HDAC1EIF2AK4CSNK1E | |
| SCHEMBL31368899 | 0.68 | LATS1 (0.39) | PRKCQLATS1HDAC1PRKD1PRKD2 | |
| SCHEMBL4441752 | 0.67 | GLA (0.39) | PRKCQLATS1HDAC1AURKAFLT3 | |
| SCHEMBL30686600 | 0.67 | PRKD1 (0.48) | PRKCQHDAC1PRKD1PRKD2EIF2AK4 | |
| Hydrochloric Acid SCHEMBL16236313 | 0.67 | ALDH1A1 (0.56) | PRKCQLATS1HDAC1EIF2AK4CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532496-A1 | NOVEL PAR-2 INHIBITORS | Domain Therapeutics (FR) | 2025-04-09 | — | — | EP | claimed |
| WO-2023233033-A1 | NOVEL PAR-2 INHIBITORS | DOMAIN THERAPEUTICS (FR) | 2023-12-07 | — | — | WO | claimed |