Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GLP1R | P43220 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27111057 | 0.88 | GLP1R (0.41) | PTGER4ACSS2LCKCNR2CNR1 | |
| SCHEMBL30686438 | 0.88 | GLP1R (0.41) | PTGER4ACSS2LCKCNR2CNR1 | |
| SCHEMBL30232970 | 0.83 | BRD4 (0.46) | CNR2CNR1 | |
| SCHEMBL24900035 | 0.77 | ACSS2 (0.47) | KDM4EACSS2LCKGLP1R | |
| SCHEMBL30020641 | 0.77 | ACSS2 (0.47) | KDM4EACSS2LCKGLP1R | |
| SCHEMBL29826815 | 0.76 | ACSS2 (0.46) | KDM4EACSS2LCKCYP3A4CYP2C9 | |
| SCHEMBL30740795 | 0.76 | ACSS2 (0.46) | KDM4EACSS2LCKCYP3A4CYP2C9 | |
| SCHEMBL24265338 | 0.75 | ACSS2 (0.46) | KDM4EACSS2LCKCYP3A4CYP2C9 | |
| SCHEMBL29826142 | 0.75 | ACSS2 (0.46) | KDM4EPTGER4ACSS2LCKALDH1A1 | |
| SCHEMBL28839348 | 0.74 | KDM4E (0.54) | KDM4EPTGER4ACSS2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242067-B | Novel aryl ether substituted heterocycles as GLP1R agonists | 杭州德睿智药科技有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-117242067-A | Novel aryl ether substituted heterocycles as GLP1R agonists | 杭州德睿智药科技有限公司 | 2023-12-15 | — | — | CN | disclosed |