SCHEMBL30686901

SCHEMBL30686901

CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCNC(=N)N)C(C)(C)C)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ NTSR1 P30989 19/20 0.72
▸ NTSR2 O95665 17/20 0.72
▸ SORT1 Q99523 17/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30038817 0.92 NTSR1 (0.63) NTSR1NTSR2SORT1
SCHEMBL29886800 0.90 NTSR2 (0.67) NTSR1NTSR2SORT1
SCHEMBL30864885 0.89 NTSR1 (0.78) NTSR1NTSR2SORT1
SCHEMBL30038534 0.89 NTSR1 (0.60) NTSR1NTSR2SORT1
SCHEMBL19682065 0.89 NTSR1 (0.58) NTSR1NTSR2SORT1
SCHEMBL12523184 0.89 NTSR1 (0.60) NTSR1NTSR2SORT1
SCHEMBL12523185 0.88 NTSR1 (0.58) NTSR1NTSR2SORT1
SCHEMBL32664435 0.87 NTSR2 (0.58) NTSR1NTSR2SORT1
SCHEMBL30943511 0.87 NMUR2 (0.58) NTSR1NTSR2SORT1
SCHEMBL19682203 0.86 NTSR1 (0.56) NTSR1NTSR2SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250276100-A1 DEVELOPMENT OF NTSR TARGETED AGENTS FOR IMAGING AND THERAPY APPLICATIONS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-09-04 — — US disclosed
EP-4518912-A1 DEVELOPMENT OF NTSR TARGETED AGENTS FOR IMAGING AND THERAPY APPLICATIONS The University of North Carolina at Chapel Hill (US) 2025-03-12 — — EP disclosed
CN-119325393-A Development of agents targeting NTSR for imaging and therapeutic applications 北卡罗来纳大学教堂山分校 2025-01-17 — — CN disclosed
WO-2023215778-A1 DEVELOPMENT OF NTSR TARGETED AGENTS FOR IMAGING AND THERAPY APPLICATIONS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-11-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250276100-A1 DEVELOPMENT OF NTSR TARGETED AGENTS FOR IMAGING AND THERAPY APPLICATIONS NTSR1, NTSR2, NPSR1 NTSR1 1/4885NTSR2 2/4885SORT1 161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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