SCHEMBL29886800

SCHEMBL29886800

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCCN)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NTSR2 O95665 12/20 0.67
▸ NTSR1 P30989 12/20 0.67
▸ SORT1 Q99523 12/20 0.67
▸ NPY4R P50391 4/20 0.61
▸ NPY1R P25929 3/20 0.61
▸ NPY2R P49146 2/20 0.61
▸ NPY5R Q15761 2/20 0.61
▸ OPRM1 P35372 2/20 0.58
▸ OPRK1 P41145 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30436277 0.93 NTSR1 (0.60) NTSR2NTSR1SORT1NPY4RNPY1R
SCHEMBL31738532 0.93 NTSR1 (0.76) NTSR2NTSR1SORT1
SCHEMBL2549334 0.90 NTSR2 (0.57) NTSR2NTSR1SORT1OPRM1OPRK1
SCHEMBL2549331 0.90 NTSR2 (0.57) NTSR2NTSR1SORT1OPRM1OPRK1
SCHEMBL29419429 0.90 OPRM1 (0.59) NTSR2NTSR1SORT1OPRM1OPRK1
SCHEMBL31634123 0.90 NTSR2 (0.60) NTSR2NTSR1SORT1NPY4ROPRM1
SCHEMBL30053247 0.90 KDM1A (0.62) NTSR2NTSR1SORT1NPY4RNPY1R
SCHEMBL32664435 0.90 NTSR2 (0.58) NTSR2NTSR1SORT1OPRM1
SCHEMBL29477118 0.90 KDM1A (0.60) NTSR2NTSR1SORT1NPY4RNPY1R
SCHEMBL30686901 0.90 NTSR1 (0.72) NTSR2NTSR1SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091097-A1 COMBINATION TREATMENT REGIMES FOR TREATING CANCER BARINTHUS BIOTHERAPEUTICS NORTH AMERICA INC (US) 2026-04-02 — — US disclosed
US-20250381281-A1 METHODS OF MANUFACTURING PEPTIDE-BASED VACCINES BARINTHUS BIOTHERAPEUTICS NORTH AMERICA INC (US) 2025-12-18 — — US disclosed
US-20250242015-A1 SELF-ASSEMBLING NANOPARTICLES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2025-07-31 — — US disclosed
US-12370255-B2 Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response BARINTHUS BIOTHERAPEUTICS NORTH AMERICA, INC. (US) 2025-07-29 — — US disclosed
US-20250127887-A1 Self-Assembling Nanoparticles Based On Amphiphilic Peptides BARINTHUS BIOTHERAPEUTICS NORTH AMERICA, INC. (US) 2025-04-24 — — US disclosed
US-20240269269-A1 Self-Assembling Nanoparticles VACCITECH NORTH AMERICA, INC. (US) 2024-08-15 — — US disclosed
CN-118103059-A Self-assembled nanoparticles based on amphiphilic peptides 巴林萨斯生物疗法北美公司 2024-05-28 — — CN disclosed
EP-4294431-A1 SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES Vaccitech North America, Inc. (US) 2023-12-27 — — EP disclosed
WO-2022177993-A1 SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES VACCITECH NORTH AMERICA, INC. (US) 2022-08-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127887-A1 Self-Assembling Nanoparticles Based On Amphiphilic Peptides IAPP, BRCA1, ANXA11 NTSR2 2402/4885NTSR1 2184/4885SORT1 1791/4885
US-20240269269-A1 Self-Assembling Nanoparticles UBE2B, CD4, UBE2G2 NTSR2 2271/4885NTSR1 1766/4885SORT1 4858/4885
US-20260091097-A1 COMBINATION TREATMENT REGIMES FOR TREATING CANCER IL2, IFNG, ICOS NTSR2 1093/4885NTSR1 1434/4885SORT1 1498/4885
US-20250242015-A1 SELF-ASSEMBLING NANOPARTICLES UBE2B, CD4, HRH1 NTSR2 2280/4885NTSR1 1763/4885SORT1 4858/4885
US-20250381281-A1 METHODS OF MANUFACTURING PEPTIDE-BASED VACCINES VIP, HM13, SPPL2B NTSR2 2537/4885NTSR1 2194/4885SORT1 1049/4885
US-12370255-B2 Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response MYD88, ICOS, CD4 NTSR2 2395/4885NTSR1 1840/4885SORT1 642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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