Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30130602 | 0.75 | FEN1 (0.46) | ALDH1A1CCR8KMT2AHSD17B10ADORA2A | |
| SCHEMBL5144248 | 0.75 | ALDH1A1 (0.48) | ALDH1A1CCR8KMT2AHSD17B10KDM4E | |
| SCHEMBL3580986 | 0.75 | FEN1 (0.46) | ALDH1A1CCR8KMT2AHSD17B10ADORA2A | |
| SCHEMBL30130601 | 0.75 | FEN1 (0.46) | ALDH1A1CCR8KMT2AHSD17B10ADORA2A | |
| SCHEMBL25427860 | 0.72 | ALDH1A1 (0.42) | ALDH1A1CCR8KMT2AHSD17B10ADORA2A | |
| SCHEMBL5598933 | 0.72 | ALDH1A1 (0.55) | ALDH1A1CCR8KMT2AHSD17B10ADORA2A | |
| SCHEMBL29545224 | 0.72 | ALDH1A1 (0.50) | ALDH1A1CCR8KMT2AHSD17B10ADORA2A | |
| SCHEMBL12338439 | 0.72 | ALDH1A1 (0.65) | ALDH1A1CCR8KMT2AHSD17B10ADORA2A | |
| SCHEMBL18450498 | 0.71 | ALDH1A1 (0.44) | ALDH1A1CCR8KMT2AHSD17B10ADORA2A | |
| SCHEMBL19153714 | 0.71 | ALDH1A1 (0.49) | ALDH1A1CCR8KMT2AHSD17B10ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12503439-B2 | Heteroaryl compounds for the treatment of pain | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-12-23 | — | — | US | disclosed |
| US-20230373925-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230373925-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | TRPV1, SCN3A, KCNN3 | ALDH1A1 1762/4885CCR8 3676/4885KMT2A 3649/4885 |
| US-12503439-B2 | Heteroaryl compounds for the treatment of pain | TRPV1, SCN3A, KCNN3 | ALDH1A1 1762/4885CCR8 3676/4885KMT2A 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.