Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 5/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.31 |
| ▸ | CBFB | Q13951 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26927992 | 0.74 | APP (0.37) | LMNASMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL24553392 | 0.72 | LMNA (0.34) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL24553962 | 0.71 | LMNA (0.37) | ALDH1A1KDM4ELMNASMN1; SMN2HPGD | |
| SCHEMBL23087826 | 0.71 | PRMT5 (0.43) | LMNAPOLB | |
| SCHEMBL29127723 | 0.70 | UCHL1 (0.33) | — | |
| SCHEMBL23087256 | 0.70 | PRMT5 (0.45) | ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL29127721 | 0.69 | — | — | |
| SCHEMBL23087293 | 0.68 | HTR2A (0.49) | LMNASMN1; SMN2 | |
| SCHEMBL30688976 | 0.68 | IRAK4 (0.31) | ALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL23099062 | 0.67 | NOTUM (0.42) | LMNAADRA2AADRA2BADRA2CKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229300-A | Preparation and application of EGFR inhibitor | 药雅科技(上海)有限公司 | 2023-12-15 | — | — | CN | disclosed |