SCHEMBL3068910

SCHEMBL3068910

O=C(c1ccc(Oc2ccc(C(=O)O)c(C(=O)O)c2)cc1)c1cccc(Oc2ccc(C(=O)O)c(C(=O)O)c2)c1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.85
HPSE Q9Y251 1/20 0.60
SRD5A2 P31213 2/20 0.58
AKR1C3 P42330 1/20 0.58
TDP1 Q9NUW8 4/20 0.54
GALK1 P51570 1/20 0.54
CASP6 P55212 1/20 0.54
MCL1 Q07820 1/20 0.54
PLEC Q15149 1/20 0.54
TNKS O95271 1/20 0.54
PARP15 Q460N3 1/20 0.54
PARP14 Q460N5 1/20 0.54
PARP10 Q53GL7 1/20 0.54
TNKS2 Q9H2K2 1/20 0.54
PARP2 Q9UGN5 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.53
PYGM P11217 1/20 0.50
APEX1 P27695 1/20 0.50
CTDSP1 Q9GZU7 1/20 0.50
CDC25A P30304 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30237450 1.00 POLB (0.85) POLBHPSESRD5A2AKR1C3TDP1
SCHEMBL3080414 0.95 POLB (0.77) POLBHPSESRD5A2AKR1C3TDP1
SCHEMBL5963366 0.92 POLB (1.00) POLBHPSESRD5A2AKR1C3TDP1
SCHEMBL423130 0.91 POLB (0.90) POLBHPSESRD5A2AKR1C3TDP1
SCHEMBL29405908 0.91 POLB (0.90) POLBHPSESRD5A2AKR1C3TDP1
SCHEMBL464972 0.87 AKR1C3 (0.71) POLBHPSEAKR1C3TDP1GALK1
SCHEMBL7168995 0.87 POLB (0.84) POLBHPSESRD5A2TDP1GALK1
SCHEMBL2868057 0.87 SRD5A2 (0.70) POLBSRD5A2AKR1C3TDP1TNKS
SCHEMBL30643036 0.87 SRD5A2 (0.70) POLBSRD5A2AKR1C3TDP1TNKS
SCHEMBL26624059 0.87 SRD5A2 (0.70) POLBSRD5A2AKR1C3TDP1TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100226016-A1 LIGHT-SHIELDING FILM NIPPON SHOKUBAI CO., LTD. (JP) 2010-09-09 US disclosed
EP-2183622-A1 LIGHT-SHIELDING FILM Nippon Shokubai Co., Ltd. (JP) 2010-05-12 EP disclosed
US-20090280339-A1 POLYIMIDE FILM, POLYIMIDE METAL LAMINATE USING SAME, AND METHOD FOR MANUFACTURING SAME MITSUI CHEMICALS ,INC. (JP) 2009-11-12 US disclosed
WO-2009014264-A1 LIGHT-SHIELDING FILM NIPPON SHOKUBAI CO., LTD. (JP) 2009-01-29 WO disclosed
US-20080299402-A1 Polyimide film, polyimide metal laminate and process for producing the same MITSUI CHEMICALS, INC. (JP) 2008-12-04 US disclosed
US-20040096679-A1 Metal laminate MITSUI CHEMICALS, INC. (JP) 2004-05-20 US disclosed
EP-1420048-A2 Metal laminate Mitsui Chemicals, Inc. (JP) 2004-05-19 EP disclosed