SCHEMBL3080414

SCHEMBL3080414

O=C(c1cccc(Oc2ccc(C(=O)O)c(C(=O)O)c2)c1)c1cccc(Oc2ccc(C(=O)O)c(C(=O)O)c2)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.77
HPSE Q9Y251 1/20 0.61
AKR1C3 P42330 1/20 0.59
TDP1 Q9NUW8 3/20 0.54
GALK1 P51570 1/20 0.54
CASP6 P55212 1/20 0.54
MCL1 Q07820 1/20 0.54
PLEC Q15149 1/20 0.54
KMO O15229 1/20 0.54
PYGM P11217 2/20 0.53
KDM4E B2RXH2 2/20 0.50
CDC25A P30304 1/20 0.50
CDC25B P30305 1/20 0.50
HSD17B10 Q99714 1/20 0.50
SRD5A2 P31213 1/20 0.50
PYGL P06737 1/20 0.50
TNKS O95271 1/20 0.50
PARP15 Q460N3 1/20 0.50
PARP14 Q460N5 1/20 0.50
PARP10 Q53GL7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30237450 0.95 POLB (0.85) POLBHPSEAKR1C3TDP1GALK1
SCHEMBL3068910 0.95 POLB (0.85) POLBHPSEAKR1C3TDP1GALK1
SCHEMBL464972 0.92 AKR1C3 (0.71) POLBHPSEAKR1C3TDP1GALK1
SCHEMBL29393214 0.88 POLB (0.67) POLBHPSEAKR1C3TDP1GALK1
SCHEMBL7637726 0.88 POLB (0.67) POLBHPSEAKR1C3TDP1GALK1
SCHEMBL140780 0.88 POLB (0.67) POLBHPSEAKR1C3TDP1GALK1
SCHEMBL3074650 0.87 POLB (0.63) POLBHPSEAKR1C3TDP1GALK1
SCHEMBL5963366 0.87 POLB (1.00) POLBHPSEAKR1C3TDP1GALK1
SCHEMBL423130 0.84 POLB (0.90) POLBHPSEAKR1C3TDP1GALK1
SCHEMBL29405908 0.84 POLB (0.90) POLBHPSEAKR1C3TDP1GALK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100226016-A1 LIGHT-SHIELDING FILM NIPPON SHOKUBAI CO., LTD. (JP) 2010-09-09 US disclosed
EP-2183622-A1 LIGHT-SHIELDING FILM Nippon Shokubai Co., Ltd. (JP) 2010-05-12 EP disclosed
US-20090280339-A1 POLYIMIDE FILM, POLYIMIDE METAL LAMINATE USING SAME, AND METHOD FOR MANUFACTURING SAME MITSUI CHEMICALS ,INC. (JP) 2009-11-12 US disclosed
WO-2009014264-A1 LIGHT-SHIELDING FILM NIPPON SHOKUBAI CO., LTD. (JP) 2009-01-29 WO disclosed
US-20080299402-A1 Polyimide film, polyimide metal laminate and process for producing the same MITSUI CHEMICALS, INC. (JP) 2008-12-04 US disclosed
US-20040096679-A1 Metal laminate MITSUI CHEMICALS, INC. (JP) 2004-05-20 US disclosed
EP-1420048-A2 Metal laminate Mitsui Chemicals, Inc. (JP) 2004-05-19 EP disclosed
US-6458912-B1 1,3-BIS(4-AMINOPHENOXY)BENZENE REPRESENTED BY THE CHEMICAL FORMULA (3) FOR PRODUCTION OF THE ABOVE POLYIMIDE, CHARACTERIZED IN THAT THE CONTENT OF AN AZO COMPOUND IS FROM 0.0 TO 0.2%. THE THERMOPLASTIC POLYIMIDE OF THE PRESENT MITSUI CHEMICALS, INC. (JP) 2002-10-01 US disclosed
EP-1090945-A1 CRYSTALLINE POLYIMIDE FOR MELT MOLDING WITH SATISFACTORY THERMAL STABILITY Mitsui Chemicals, Inc. (JP) 2001-04-11 EP disclosed