SCHEMBL30689302

SCHEMBL30689302

C=C(Cc1nc(-c2ccc(Oc3ccc(C(F)(F)F)cn3)cc2)no1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 1/20 0.49
▸ RAB9A P51151 1/20 0.48
▸ LMNA P02545 1/20 0.48
▸ SCN9A Q15858 7/20 0.48
▸ GSTP1 P09211 4/20 0.47
▸ FPR2 P25090 1/20 0.46
▸ LIPE Q05469 1/20 0.46
▸ MAPT P10636 3/20 0.45
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ CYP3A4 P08684 1/20 0.45
▸ GAA P10253 1/20 0.45
▸ CYP2C9 P11712 1/20 0.45
▸ CYP2C19 P33261 1/20 0.45
▸ HTT P42858 1/20 0.45
▸ NPSR1 Q6W5P4 1/20 0.45
▸ PKM P14618 1/20 0.44
▸ XBP1 P17861 1/20 0.44
▸ TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30689328 0.86 FFAR1 (0.43) FFAR1LMNASCN9AGSTP1MAPT
SCHEMBL30689438 0.85 LMNA (0.51) RAB9ALMNAGSTP1MAPTTP53
SCHEMBL30689299 0.84 FFAR1 (0.51) FFAR1RAB9ALMNASCN9AFPR2
SCHEMBL30689424 0.83 TP53 (0.43) FFAR1RAB9ALMNAGSTP1MAPT
SCHEMBL30689351 0.83 FFAR1 (0.41) FFAR1LMNAGSTP1MAPTSMN1; SMN2
SCHEMBL30689345 0.83 FFAR1 (0.45) FFAR1RAB9ALMNAGSTP1MAPT
SCHEMBL30689300 0.83 GSTP1 (0.45) FFAR1LMNAGSTP1MAPTSMN1; SMN2
SCHEMBL30689303 0.83 TP53 (0.42) FFAR1LMNAGSTP1MAPTSMN1; SMN2
SCHEMBL30689366 0.82 SCN9A (0.44) FFAR1RAB9ALMNASCN9AGSTP1
SCHEMBL30689322 0.81 LMNA (0.47) FFAR1LMNASCN9AGSTP1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543875-A1 OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES Sitryx Therapeutics Limited (GB) 2025-04-30 — — EP disclosed
WO-2023247958-A1 OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES SITRYX THERAPEUTICS LIMITED (GB) 2023-12-28 — — WO disclosed
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