Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30689438 | 0.87 | LMNA (0.51) | TP53MITFNCOA3LMNAMAPT | |
| SCHEMBL30689423 | 0.86 | TP53 (0.41) | TP53MITFNCOA3LMNAMAPT | |
| SCHEMBL30689424 | 0.85 | TP53 (0.43) | TP53MITFNCOA3LMNAMAPT | |
| SCHEMBL30689302 | 0.83 | FFAR1 (0.49) | TP53LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL30689323 | 0.82 | TP53 (0.42) | TP53MITFNCOA3LMNAKMT2A | |
| SCHEMBL30689347 | 0.81 | IP6K1 (0.48) | TP53MITFNCOA3LMNAATM | |
| SCHEMBL31528007 | 0.80 | MITF (0.43) | TP53MITFNCOA3LMNAKMT2A | |
| SCHEMBL30689419 | 0.79 | FFAR1 (0.53) | TP53MITFNCOA3LMNAMEN1 | |
| SCHEMBL30689370 | 0.79 | TP53 (0.42) | TP53MITFNCOA3LMNAMAPT | |
| SCHEMBL30689328 | 0.79 | FFAR1 (0.43) | TP53MITFNCOA3LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543875-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | Sitryx Therapeutics Limited (GB) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247958-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-28 | — | — | WO | disclosed |