Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 11/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680670 | 1.00 | KDM4E (0.59) | KDM4EALDH1A1SMN1; SMN2MAOBFFAR1 | |
| SCHEMBL3626120 | 0.86 | MAOB (0.54) | KDM4EALDH1A1SMN1; SMN2MAOBFFAR1 | |
| SCHEMBL2990174 | 0.86 | CYP19A1 (0.52) | KDM4EALDH1A1SMN1; SMN2MAOBFFAR1 | |
| SCHEMBL2246114 | 0.85 | FFAR1 (0.49) | KDM4EALDH1A1SMN1; SMN2MAOBFFAR1 | |
| SCHEMBL13248358 | 0.84 | ALOX5AP (0.53) | KDM4EALDH1A1SMN1; SMN2MAOBFFAR1 | |
| SCHEMBL27796956 | 0.83 | ALDH1A1 (0.64) | KDM4EALDH1A1SMN1; SMN2MAOBCYP11B1 | |
| SCHEMBL28418292 | 0.82 | MAOB (0.50) | KDM4EALDH1A1SMN1; SMN2MAOBFFAR1 | |
| SCHEMBL6445371 | 0.81 | KCNH2 (0.67) | KDM4EALDH1A1SMN1; SMN2MAOBFFAR1 | |
| Water SCHEMBL9719872 | 0.81 | PARP10 (0.62) | KDM4EALDH1A1SMN1; SMN2MAOBPARP10 | |
| SCHEMBL22874534 | 0.80 | PARP10 (0.66) | KDM4EALDH1A1SMN1; SMN2MAOBPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119968366-A | Oxadiazole derivatives, methods of preparation and use thereof in the treatment of inflammatory diseases | 西特瑞治疗有限公司 | 2025-05-09 | — | — | CN | disclosed |
| EP-4543875-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | Sitryx Therapeutics Limited (GB) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247958-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-28 | — | — | WO | disclosed |