Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TLR4 | O00206 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10388636 | 0.92 | KDM4E (0.63) | KCNH2ALDH1A1SMN1; SMN2KDM4EPARP10 | |
| SCHEMBL1312722 | 0.88 | SMN1; SMN2 (0.62) | KCNH2ALDH1A1SMN1; SMN2KDM4EPARP10 | |
| SCHEMBL22874534 | 0.86 | PARP10 (0.66) | KCNH2ALDH1A1SMN1; SMN2KDM4EPARP10 | |
| SCHEMBL5667052 | 0.84 | KDM4E (0.63) | KCNH2ALDH1A1SMN1; SMN2KDM4EPARP10 | |
| SCHEMBL22967393 | 0.84 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2KDM4EPARP10CYP1A2 | |
| SCHEMBL17712563 | 0.84 | SMN1; SMN2 (0.63) | KCNH2ALDH1A1SMN1; SMN2KDM4EPARP10 | |
| SCHEMBL21568937 | 0.84 | KDM4E (0.63) | KCNH2ALDH1A1SMN1; SMN2KDM4EPARP10 | |
| SCHEMBL864159 | 0.84 | KDM4E (0.58) | KCNH2ALDH1A1SMN1; SMN2KDM4EPARP10 | |
| SCHEMBL1073540 | 0.84 | SYK (0.68) | ALDH1A1SMN1; SMN2KDM4EPARP10CYP1A2 | |
| SCHEMBL169753 | 0.84 | SMN1; SMN2 (0.63) | ALDH1A1SMN1; SMN2KDM4EPARP10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100383138-C | N-monoacetyl o-phenylenediamines, their fused heterocyclic derivatives and their use as medicaments | HOFFMANN LA ROCHE (CH) | 2008-04-23 | — | — | CN | claimed |
| CN-1747948-A | Novel n-monoacylated o-phenylenediamines, their condensed heterocyclic derivatives and their use as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 2006-03-15 | — | — | CN | claimed |
| US-6156774-A | Beta-thiopropionyl-amino acid derivatives and their use as beta-lactamase inhibitors | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-12-05 | — | — | US | claimed |
| EP-1000024-A1 | MERCAPTOACYLAMINO ACIDS AS METALLO-BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 2000-05-17 | — | — | EP | claimed |
| EP-0970062-A2 | PYRROLIDINE AND THIAZOLE DERIVATIVES WITH METALLO-BETA-LACTAMASE INHIBITORY PROPERTIES | SMITHKLINE BEECHAM PLC (GB) | 2000-01-12 | — | — | EP | claimed |
| WO-1999006365-A1 | MERCAPTOACYLAMINO ACIDS AS METALLO-BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1999-02-11 | — | — | WO | claimed |
| WO-1998040056-A2 | PYRROLIDINE AND THIAZOLE DERIVATIVES WITH METALLO-BETA-LACTAMASE INHIBITORY PROPERTIES | SMITHKLINE BEECHAM PLC (GB) | 1998-09-17 | — | — | WO | claimed |
| US-5468721-A | FOR CONTROLLING OR KILLING WEEDS | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1995-11-21 | — | — | US | claimed |
| CN-116063226-B | Ether compound containing monoterpene phenol structure | 云南省农业科学院茶叶研究所 | 2023-06-02 | — | — | CN | disclosed |
| CN-116063226-B | Ether compound containing monoterpene phenol structure | 云南省农业科学院茶叶研究所 | 2023-06-02 | — | — | CN | disclosed |
| CN-116063226-A | Ether compound containing monoterpene phenol structure | 云南省农业科学院茶叶研究所 | 2023-05-05 | — | — | CN | disclosed |
| CN-116063226-A | Ether compound containing monoterpene phenol structure | 云南省农业科学院茶叶研究所 | 2023-05-05 | — | — | CN | disclosed |
| WO-2023062627-A1 | HERBICIDES AND USE THEREOF | PROJINI AGCHEM LTD (IL) | 2023-04-20 | — | — | WO | disclosed |
| US-20220196685-A1 | PROBES FOR DETECTION OF COPPER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-06-23 | — | — | US | disclosed |
| WO-1998017639-A1 | BETA-THIOPROPIONYL-AMINO ACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1998-04-30 | — | — | WO | disclosed |
| US-4839369-A | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | RORER PHARMACEUTICAL CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |
| US-4728668-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORPORATION (US) | 1988-03-01 | — | — | US | disclosed |
| US-4725619-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORPORATION (US) | 1988-02-16 | — | — | US | disclosed |
| US-4631287-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORP. (US) | 1986-12-23 | — | — | US | disclosed |
| US-4243807-A | CHEMICAL INTERMEDIATES FOR HYPOTENSIVE AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1981-01-06 | — | — | US | disclosed |