Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30689323 | 0.87 | TP53 (0.42) | LMNAATMRAB9ATP53GSTP1 | |
| SCHEMBL30689449 | 0.87 | LMNA (0.44) | LMNAATMTSHRTP53GSTP1 | |
| SCHEMBL30689336 | 0.85 | LMNA (0.43) | LMNAATMTSHRTP53GSTP1 | |
| SCHEMBL30689383 | 0.85 | TP53 (0.41) | LMNAATMTP53GSTP1MITF | |
| SCHEMBL30689347 | 0.84 | IP6K1 (0.48) | LMNAATMRAB9ATSHRTP53 | |
| SCHEMBL31527959 | 0.83 | LMNA (0.42) | LMNAATMRAB9ATSHRNFKB1 | |
| SCHEMBL30689424 | 0.81 | TP53 (0.43) | LMNAATMRAB9ATSHRNFKB1 | |
| SCHEMBL31527827 | 0.81 | TP53 (0.46) | LMNAATMRAB9ATP53GSTP1 | |
| SCHEMBL30689438 | 0.80 | LMNA (0.51) | LMNAATMRAB9ATSHRTP53 | |
| SCHEMBL31527955 | 0.80 | LMNA (0.46) | LMNAATMRAB9ATSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543875-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | Sitryx Therapeutics Limited (GB) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247958-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-28 | — | — | WO | disclosed |