Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30689408 | 0.88 | TP53 (0.39) | TP53LMNAATMACACBALDH1A1 | |
| SCHEMBL30689336 | 0.87 | LMNA (0.43) | TP53LMNAATMACACBALDH1A1 | |
| SCHEMBL30689323 | 0.87 | TP53 (0.42) | TP53LMNAATMACACBALDH1A1 | |
| SCHEMBL30689392 | 0.85 | LMNA (0.44) | TP53LMNAATMACACBALDH1A1 | |
| SCHEMBL30689449 | 0.83 | LMNA (0.44) | TP53LMNAATMACACBALDH1A1 | |
| SCHEMBL30689347 | 0.80 | IP6K1 (0.48) | TP53LMNAATMACACBALDH1A1 | |
| SCHEMBL31527959 | 0.79 | LMNA (0.42) | TP53LMNAATMACACBALDH1A1 | |
| SCHEMBL30689303 | 0.78 | TP53 (0.42) | TP53LMNAATMACACBALDH1A1 | |
| SCHEMBL30689424 | 0.77 | TP53 (0.43) | TP53LMNAATMACACBMAPT | |
| SCHEMBL31527827 | 0.77 | TP53 (0.46) | TP53LMNAATMACACBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543875-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | Sitryx Therapeutics Limited (GB) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247958-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-28 | — | — | WO | disclosed |