Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30689309 | 0.88 | LMNA (0.39) | LMNAATMTSHRNFKB1RAB9A | |
| SCHEMBL30689448 | 0.84 | LMNA (0.43) | LMNAATMTSHRNFKB1RAB9A | |
| SCHEMBL30689367 | 0.82 | NOTUM (0.50) | LMNAATMTSHRNFKB1RAB9A | |
| SCHEMBL30689335 | 0.81 | LMNA (0.49) | LMNAATMTSHRNFKB1RAB9A | |
| SCHEMBL31527908 | 0.81 | FFAR1 (0.42) | LMNAATMTSHRTP53MITF | |
| SCHEMBL30689384 | 0.80 | TSHR (0.42) | LMNAATMTSHRNFKB1RAB9A | |
| SCHEMBL30689419 | 0.79 | FFAR1 (0.53) | LMNAATMTSHRNFKB1RAB9A | |
| SCHEMBL31527955 | 0.79 | LMNA (0.46) | LMNAATMTSHRNFKB1RAB9A | |
| SCHEMBL25802136 | 0.79 | MAPT (0.53) | LMNAATMTSHRRAB9AFFAR1 | |
| SCHEMBL30689392 | 0.78 | LMNA (0.44) | LMNAATMTSHRNFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119968366-A | Oxadiazole derivatives, methods of preparation and use thereof in the treatment of inflammatory diseases | 西特瑞治疗有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119968366-A | Oxadiazole derivatives, methods of preparation and use thereof in the treatment of inflammatory diseases | 西特瑞治疗有限公司 | 2025-05-09 | — | — | CN | disclosed |
| EP-4543875-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | Sitryx Therapeutics Limited (GB) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247958-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-28 | — | — | WO | disclosed |