Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.39 |
| ▸ | NPC1 | O15118 | 8/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30689344 | 0.84 | NOTUM (0.40) | RAB9ANPC1SMN1; SMN2GAAPPARG | |
| SCHEMBL30689433 | 0.81 | IP6K1 (0.39) | RAB9ANPC1SMN1; SMN2GAAPPARG | |
| SCHEMBL30689395 | 0.80 | PTGS2 (0.39) | RAB9ANPC1SMN1; SMN2GAAPPARG | |
| SCHEMBL30689444 | 0.79 | SCN7A (0.38) | PPARGMAPTPTGS2CNR1CNR2 | |
| SCHEMBL31527971 | 0.74 | IP6K1 (0.38) | RAB9ANPC1SMN1; SMN2PPARGMAPT | |
| SCHEMBL4056084 | 0.68 | ADAMTS4 (0.48) | RAB9ANPC1SMN1; SMN2PPARGHPGD | |
| SCHEMBL30689325 | 0.68 | NOTUM (0.42) | RAB9ANPC1SMN1; SMN2GAACASP3 | |
| SCHEMBL31527877 | 0.67 | GSTP1 (0.44) | RAB9ANPC1SMN1; SMN2GAAPPARG | |
| SCHEMBL31527931 | 0.65 | MAPT (0.42) | SMN1; SMN2GAAPPARGMAPTHPGD | |
| SCHEMBL31527956 | 0.65 | GSTP1 (0.43) | RAB9ANPC1SMN1; SMN2PPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543875-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | Sitryx Therapeutics Limited (GB) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247958-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-28 | — | — | WO | disclosed |