Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 10/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.36 |
| ▸ | CDK4 | P11802 | 2/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 8/20 | 0.35 |
| ▸ | ATRIP | Q8WXE1 | 8/20 | 0.35 |
| ▸ | ATM | Q13315 | 7/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 3/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541721 | 1.00 | PRKDC (0.36) | PRKDCPIK3CBCDK4CSF1RCDK6 | |
| SCHEMBL21541860 | 0.90 | PRKDC (0.47) | PRKDCPIK3CBCDK4CSF1RCDK6 | |
| SCHEMBL21541743 | 0.88 | PRKDC (0.47) | PRKDCPIK3CBCDK4CSF1RCDK6 | |
| SCHEMBL21541857 | 0.87 | CDK4 (0.35) | CDK4CSF1RCDK6PDE3BPDE3A | |
| SCHEMBL21541733 | 0.86 | CDK4 (0.37) | CDK4CSF1RCDK6PDE3BPDE3A | |
| SCHEMBL21541716 | 0.83 | CDK4 (0.34) | CDK4CSF1RCDK6PDE3BPDE3A | |
| SCHEMBL21541808 | 0.83 | S1PR1 (0.37) | CDK4CSF1RCDK6PDE3BPDE3A | |
| SCHEMBL21541779 | 0.81 | CDK4 (0.35) | CDK4CSF1RCDK6ATRATM | |
| SCHEMBL29558902 | 0.81 | CDK4 (0.35) | CDK4CSF1RCDK6ATRATM | |
| SCHEMBL21541837 | 0.81 | PRKDC (0.47) | PRKDCPIK3CBCDK4CSF1RCDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567041-B1 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2023-12-27 | — | — | EP | disclosed |