Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828026 | 1.00 | CES1 (0.39) | CES1AKR1B1CES2ALOX15ALDH1A1 | |
| SCHEMBL9639802 | 1.00 | CES1 (0.39) | CES1AKR1B1CES2ALOX15ALDH1A1 | |
| SCHEMBL11361617 | 0.83 | CA2 (0.43) | CES2ALOX15ALDH1A1KDM4EMEN1 | |
| SCHEMBL11889792 | 0.83 | MAPT (0.38) | CES1CES2ALOX15ALDH1A1MAPK1 | |
| SCHEMBL3227911 | 0.83 | ALDH1A1 (0.41) | CES1CES2ALOX15ALDH1A1KDM4E | |
| SCHEMBL10711481 | 0.83 | CA2 (0.41) | CES1CES2ALOX15ALDH1A1KDM4E | |
| SCHEMBL6912635 | 0.83 | ALDH1A1 (0.41) | CES1CES2ALOX15ALDH1A1KDM4E | |
| SCHEMBL9456919 | 0.81 | KMT2A (0.41) | CES1CES2ALDH1A1KEAP1FFAR1 | |
| SCHEMBL9456923 | 0.81 | KMT2A (0.41) | CES1CES2ALDH1A1KEAP1FFAR1 | |
| SCHEMBL9457024 | 0.81 | KMT2A (0.41) | CES1CES2ALDH1A1KEAP1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110128376-B | Compound, preparation method and application of compound as latent epoxy curing agent | 万华化学集团股份有限公司 | 2020-11-20 | — | — | CN | claimed |
| CN-110128376-A | A kind of compound and preparation method and its purposes as resting form epoxy hardener | 万华化学集团股份有限公司 | 2019-08-16 | — | — | CN | claimed |
| JP-52078892-A | — | — | None | — | — | JP | disclosed |
| CN-117778339-A | Sulfoxide reductase mutant and application thereof in preparation of chiral sulfoxide and sulfinyl ester | 遵义医科大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-114829447-A | Brush prodrug and use thereof | 麻省理工学院 | 2022-07-29 | — | — | CN | disclosed |
| CN-112656954-A | Lipid formulations for delivery of messenger RNA | 夏尔人类遗传性治疗公司 | 2021-04-16 | — | — | CN | disclosed |
| CN-112618732-A | Lipid formulations for delivery of messenger RNA | 夏尔人类遗传性治疗公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-105813656-B | Lipid formulations for delivery of messenger RNA | 夏尔人类遗传性治疗公司 | 2021-01-15 | — | — | CN | disclosed |
| CN-110128376-B | Compound, preparation method and application of compound as latent epoxy curing agent | 万华化学集团股份有限公司 | 2020-11-20 | — | — | CN | disclosed |
| CN-110128376-A | A kind of compound and preparation method and its purposes as resting form epoxy hardener | 万华化学集团股份有限公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-109619269-A | Special feed for sea cucumber cultured in net cage | 浙江海洋大学 | 2019-04-16 | — | — | CN | disclosed |
| US-4595532-A | N-(substituted-methyl)-azetidin-2-ones | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1986-06-17 | — | — | US | disclosed |
| EP-0116432-A2 | Improvements in or relating to N-(substituted-methyl)-azetidin-2-ones | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1984-08-22 | — | — | EP | disclosed |
| EP-0021177-B1 | MAYTANSINOIDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1984-02-08 | — | — | EP | disclosed |
| US-4308268-A | ANTITUMOR, ANTIMITOTIC, FUNGICIDES, ANTIPROTOZOA AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4245107-A | ANTIBIOTICS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1981-01-13 | — | — | US | disclosed |
| EP-0021177-A1 | Maytansinoids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |
| US-4229573-A | BACTERICIDES | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1980-10-21 | — | — | US | disclosed |
| US-4172197-A | BACTERICIDES | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1979-10-23 | — | — | US | disclosed |
| JP-S5278892-A | PREPARATION OF PENICILLINS AND CEPHALOSPORINS HAVING PHENYLSULFINYL FR OOPGROOP | ASAHI CHEM IND CO LTD | 1977-07-02 | — | — | JP | disclosed |