Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD74 | P04233 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.52 |
| ▸ | IDO1 | P14902 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CBX7 | O95931 | 4/20 | 0.46 |
| ▸ | CDYL | Q9Y232 | 4/20 | 0.46 |
| ▸ | CDYL2 | Q8N8U2 | 3/20 | 0.46 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5252825 | 1.00 | CD74 (0.53) | CD74MIFGPR55IDO1KMT2A | |
| SCHEMBL5539787 | 0.85 | MEN1 (0.59) | GPR55KMT2AMEN1LMNATP53 | |
| SCHEMBL434086 | 0.79 | MIF (0.54) | CD74MIFKMT2AMEN1LMNA | |
| SCHEMBL9372564 | 0.79 | ATM (0.53) | CD74MIFGPR55IDO1KMT2A | |
| SCHEMBL5546434 | 0.78 | CD74 (0.53) | CD74MIFIDO1KMT2ACBX7 | |
| SCHEMBL399737 | 0.78 | DDB1 (0.46) | GPR55KMT2ALMNAPKMDDB1 | |
| SCHEMBL5544722 | 0.78 | IDO1 (0.57) | IDO1TP53PKMALDH1A1 | |
| SCHEMBL614398 | 0.78 | SIGMAR1 (0.47) | GPR55CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL18940725 | 0.78 | DDB1 (0.46) | GPR55KMT2AMEN1LMNAPKM | |
| SCHEMBL3330251 | 0.78 | PKM (0.49) | CD74MIFPKMDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304205-A | Benzimidazole ternary fused ring compound, pharmaceutically acceptable salt thereof and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-12-29 | — | — | CN | disclosed |