Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | BAX | Q07812 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893240 | 0.84 | RAD52 (0.46) | KDM1ARAD52POLBKDM4ELMNA | |
| SCHEMBL7755648 | 0.82 | KDM1A (0.55) | KDM1ADNM1POLBKDM4ELMNA | |
| SCHEMBL8616272 | 0.79 | KMT2A (0.64) | KDM1ADNM1LMNAALDH1A1HTT | |
| SCHEMBL8371648 | 0.77 | KDM1A (0.51) | KDM1ADNM1KDM4ELMNAALDH1A1 | |
| SCHEMBL8616275 | 0.77 | KDM1A (0.51) | KDM1ADNM1MEN1KMT2A | |
| SCHEMBL8371646 | 0.77 | KDM1A (0.51) | KDM1ADNM1KDM4ELMNAALDH1A1 | |
| SCHEMBL12473966 | 0.76 | RAD52 (0.56) | RAD52POLBKDM4ELMNAALDH1A1 | |
| SCHEMBL7458831 | 0.76 | LMNA (0.56) | KDM4ELMNASMN1; SMN2HTTCYP3A4 | |
| Hydrochloric Acid SCHEMBL5551352 | 0.75 | RAD52 (0.49) | RAD52POLBKDM4ELMNAALDH1A1 | |
| SCHEMBL8617252 | 0.75 | KDM1A (0.49) | KDM1ADNM1MEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11080142-A | — | — | None | — | — | JP | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |
| JP-H1180142-A | PRODUCTION OF DIPHENYLALKYL COMPOUND | POLA CHEM IND INC | 1999-03-26 | — | — | JP | disclosed |