Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR5A | P47898 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3069013 | 0.84 | KDM1A (0.55) | RAD52CYP3A4ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8891364 | 0.76 | CASP1 (0.49) | ALDH1A1HSD17B10KDM4EMAPTMAPK1 | |
| SCHEMBL8890641 | 0.76 | ABCB1 (0.50) | ALDH1A1POLBKDM4EMAPTMAPK1 | |
| SCHEMBL6697306 | 0.75 | SMN1; SMN2 (0.71) | HSD17B10POLBSMN1; SMN2KDM4EMAPT | |
| SCHEMBL24323728 | 0.75 | SMN1; SMN2 (0.71) | HSD17B10POLBSMN1; SMN2KDM4EMAPT | |
| SCHEMBL8891784 | 0.73 | HRH4 (0.45) | ALDH1A1HSD17B10KDM4EMAPTMAPK1 | |
| SCHEMBL31536986 | 0.69 | TRPV4 (0.45) | ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL31536985 | 0.69 | DRD2 (0.48) | CASR | |
| SCHEMBL31536981 | 0.69 | USP2 (0.46) | SLC6A4SMN1; SMN2KDM4ETP53MAPT | |
| SCHEMBL12473966 | 0.67 | RAD52 (0.56) | RAD52SLC6A4ALDH1A1POLBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014685-A1 | PYRIMIDINE DERIVATIVES | GYÓGYSZERKUTATÓ INTÉZET KFT (HU) | 1997-04-24 | — | — | WO | disclosed |