Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.55 |
| ▸ | BRD4 | O60885 | 14/20 | 0.54 |
| ▸ | EDNRB | P24530 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690118 | 0.73 | BRD4 (0.45) | BRD4ALDH1A1 | |
| SCHEMBL28736608 | 0.72 | BRD4 (0.53) | EDNRABRD4EDNRBALDH1A1KEAP1 | |
| SCHEMBL30522027 | 0.72 | BRD4 (0.53) | EDNRABRD4EDNRBALDH1A1KEAP1 | |
| SCHEMBL26376309 | 0.70 | POLB (0.56) | EDNRAALDH1A1POLB | |
| SCHEMBL7229182 | 0.70 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL9760642 | 0.69 | ALDH1A1 (0.62) | ALDH1A1POLB | |
| SCHEMBL29833241 | 0.67 | BRD4 (1.00) | EDNRABRD4EDNRB | |
| SCHEMBL22374688 | 0.67 | BRD4 (1.00) | EDNRABRD4EDNRB | |
| SCHEMBL6674669 | 0.67 | LMNA (0.67) | ALDH1A1POLB | |
| SCHEMBL6674388 | 0.67 | LMNA (0.67) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304205-A | Benzimidazole ternary fused ring compound, pharmaceutically acceptable salt thereof and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-12-29 | — | — | CN | disclosed |