Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.37 |
| ▸ | CDK9 | P50750 | 5/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 4/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690653 | 0.88 | KIT (0.44) | KITCCNT1CDK9WNT3ABTK | |
| SCHEMBL30690767 | 0.87 | KIT (0.45) | KITLMNAMAPTWNT3ABTK | |
| SCHEMBL30690444 | 0.84 | KIT (0.40) | KITLMNAMAPTPARP1TERT | |
| SCHEMBL30690732 | 0.83 | KIT (0.41) | KITLMNAMAPTWNT3APARP1 | |
| SCHEMBL30690620 | 0.81 | GSK3B (0.45) | KITLMNAMAPTPARP1TERT | |
| SCHEMBL30690654 | 0.81 | GSK3B (0.46) | KITLMNAMAPTPARP1SMN1; SMN2 | |
| SCHEMBL30690587 | 0.81 | GSK3B (0.46) | KITLMNAMAPTPARP1SMN1; SMN2 | |
| SCHEMBL27273394 | 0.81 | GSK3B (0.46) | KITLMNAMAPTPARP1SMN1; SMN2 | |
| SCHEMBL30690440 | 0.81 | PARP1 (0.37) | KITLMNAMAPTPARP1TERT | |
| SCHEMBL30690505 | 0.79 | KDR (0.40) | KITLMNAMAPTPARP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | claimed |