SCHEMBL30690767 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	KIT	P10721	2/20	0.45

▸	ULK1	O75385	1/20	0.40

▸	BTK	Q06187	4/20	0.38

▸	PARP1	P09874	2/20	0.37

▸	MAPT	P10636	2/20	0.36

▸	LMNA	P02545	2/20	0.36

▸	SMN1; SMN2	Q16637	1/20	0.36

▸	KDR	P35968	1/20	0.35

▸	WNT3A	P56704	1/20	0.35

▸	TERT	O14746	1/20	0.35

▸	GAA	P10253	1/20	0.35

▸	ALDH1A1	P00352	2/20	0.34

▸	MEN1	O00255	1/20	0.34

▸	KMT2A	Q03164	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30690690	0.90	KIT (0.43)	KITULK1BTKWNT3A
SCHEMBL30690442	0.90	KIT (0.41)	KITULK1BTKWNT3A
SCHEMBL30690732	0.89	KIT (0.41)	KITPARP1MAPTLMNASMN1; SMN2
SCHEMBL30690444	0.89	KIT (0.40)	KITPARP1MAPTLMNASMN1; SMN2
SCHEMBL30690542	0.88	KIT (0.39)	KITULK1BTK
SCHEMBL30690482	0.88	KIT (0.41)	KITULK1BTKSMN1; SMN2GAA
SCHEMBL30690484	0.87	KIT (0.48)	KITBTKPARP1MAPTLMNA
SCHEMBL30690654	0.82	GSK3B (0.46)	KITPARP1MAPTLMNASMN1; SMN2
SCHEMBL30690508	0.82	PARP1 (0.41)	PARP1MAPTLMNASMN1; SMN2WNT3A
SCHEMBL30690587	0.82	GSK3B (0.46)	KITPARP1MAPTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023247593-A1	PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS	ACTELION PHARMACEUTICALS LTD (CH)	2023-12-28	—	—	WO	claimed