Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 3/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690767 | 0.89 | KIT (0.45) | KITPARP1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30690444 | 0.86 | KIT (0.40) | KITPARP1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30690484 | 0.83 | KIT (0.48) | KITPARP1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30690508 | 0.82 | PARP1 (0.41) | PARP1LMNAMAPTSMN1; SMN2WNT3A | |
| SCHEMBL30690587 | 0.82 | GSK3B (0.46) | KITPARP1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30690654 | 0.82 | GSK3B (0.46) | KITPARP1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30690620 | 0.82 | GSK3B (0.45) | KITPARP1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL27273394 | 0.82 | GSK3B (0.46) | KITPARP1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30690688 | 0.81 | PDGFRA (0.37) | KIT | |
| SCHEMBL30690504 | 0.81 | HRH3 (0.39) | KITSMN1; SMN2ALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | claimed |