Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 5/20 | 0.46 |
| ▸ | GSK3B | P49841 | 5/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.46 |
| ▸ | KIT | P10721 | 4/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TERT | O14746 | 2/20 | 0.37 |
| ▸ | MLLT1 | Q03111 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690515 | 0.97 | WNT1 (0.46) | WNT1GSK3BDYRK1AKITCSF1R | |
| SCHEMBL30690661 | 0.97 | WNT1 (0.46) | WNT1GSK3BDYRK1AKITCSF1R | |
| SCHEMBL30690637 | 0.97 | WNT1 (0.46) | WNT1GSK3BDYRK1AKITCSF1R | |
| SCHEMBL30690664 | 0.95 | GSK3B (0.49) | WNT1GSK3BDYRK1AKITCSF1R | |
| SCHEMBL30690548 | 0.95 | GSK3B (0.49) | WNT1GSK3BDYRK1AKITCSF1R | |
| SCHEMBL27274304 | 0.88 | GSK3B (0.46) | WNT1GSK3BDYRK1AKITCSF1R | |
| SCHEMBL30690479 | 0.88 | GSK3B (0.42) | WNT1GSK3BDYRK1AKITCSF1R | |
| SCHEMBL30690698 | 0.87 | WNT1 (0.51) | WNT1GSK3BDYRK1ATERTMLLT1 | |
| SCHEMBL30690439 | 0.87 | KIT (0.41) | WNT1GSK3BDYRK1AKITCSF1R | |
| SCHEMBL30690747 | 0.87 | KIT (0.41) | WNT1GSK3BDYRK1AKITCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | claimed |