Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.49 |
| ▸ | WNT1 | P04628 | 6/20 | 0.49 |
| ▸ | KIT | P10721 | 4/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | MLLT1 | Q03111 | 5/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690548 | 1.00 | GSK3B (0.49) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL30690515 | 0.98 | WNT1 (0.46) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL30690637 | 0.98 | WNT1 (0.46) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL30690661 | 0.98 | WNT1 (0.46) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL30690649 | 0.95 | WNT1 (0.46) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL30690479 | 0.93 | GSK3B (0.42) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL30690695 | 0.92 | GSK3B (0.48) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL30690761 | 0.92 | KIT (0.41) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL30690719 | 0.91 | KIT (0.40) | GSK3BDYRK1AWNT1KITCSF1R | |
| SCHEMBL30690588 | 0.91 | GSK3B (0.40) | GSK3BDYRK1AWNT1KITCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | claimed |