Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | WNT1 | P04628 | 6/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
| ▸ | CLK2 | P49760 | 2/20 | 0.34 |
| ▸ | CLK3 | P49761 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690679 | 0.92 | PDGFRA (0.40) | PDGFRACHRM1HRH3CSF1RKIT | |
| SCHEMBL30690781 | 0.89 | PDGFRA (0.39) | PDGFRACHRM1HRH3CSF1RKIT | |
| Hydrochloric Acid SCHEMBL30690806 | 0.89 | PDGFRA (0.38) | PDGFRACHRM1HRH3CSF1RKIT | |
| SCHEMBL30690760 | 0.86 | CSF1R (0.40) | PDGFRACHRM1HRH3CSF1RKIT | |
| SCHEMBL30690685 | 0.85 | PDGFRA (0.42) | PDGFRACHRM1HRH3CSF1RKIT | |
| SCHEMBL30690642 | 0.85 | CSF1R (0.41) | PDGFRACHRM1HRH3CSF1RKIT | |
| SCHEMBL30690812 | 0.84 | PDGFRA (0.60) | PDGFRACHRM1HRH3CSF1RKIT | |
| SCHEMBL30690774 | 0.83 | GSK3B (0.41) | PDGFRACHRM1HRH3CSF1RKIT | |
| SCHEMBL30690658 | 0.83 | CSF1R (0.40) | PDGFRACHRM1HRH3CSF1RKIT | |
| SCHEMBL30690764 | 0.80 | CHEK1 (0.39) | WNT1DYRK1AGSK3BCLK2CLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |