Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | GSK3B | P49841 | 4/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.32 |
| ▸ | WNT1 | P04628 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690687 | 0.87 | PIK3CA (0.32) | HDAC3HDAC1HDAC2 | |
| SCHEMBL30690763 | 0.87 | GSK3B (0.36) | HRH3GSK3BDYRK1AWNT1HDAC3 | |
| SCHEMBL30690797 | 0.86 | GSK3B (0.44) | HRH3GSK3BDYRK1AWNT1HDAC3 | |
| SCHEMBL30690779 | 0.84 | GSK3B (0.35) | HRH3GSK3BDYRK1AWNT1HDAC3 | |
| SCHEMBL30690782 | 0.84 | ABL1 (0.32) | HDAC3HDAC1HDAC2 | |
| SCHEMBL30690780 | 0.82 | HDAC3 (0.34) | HDAC3HDAC1HDAC2 | |
| SCHEMBL30690482 | 0.81 | KIT (0.41) | HRH3GSK3BDYRK1AWNT1RECQL | |
| SCHEMBL30690691 | 0.76 | AURKB (0.37) | HRH3GSK3BDYRK1AWNT1 | |
| SCHEMBL30690504 | 0.75 | HRH3 (0.39) | HRH3GSK3BDYRK1AWNT1MCHR1 | |
| SCHEMBL30690792 | 0.75 | PIK3CD (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |