Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | KDM4B | O94953 | 1/20 | 0.50 |
| ▸ | KDM5C | P41229 | 1/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.50 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MARK3 | P27448 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL243725 | 1.00 | PARP1 (0.53) | PARP1KDM4CKDM4AKDM4BKDM5C | |
| Bromide SCHEMBL2246198 | 0.98 | PARP1 (0.52) | PARP1KDM4CKDM4AKDM4BKDM5C | |
| SCHEMBL1159186 | 0.84 | PARP1 (0.53) | PARP1KDM4CKDM4AKDM4BKDM5C | |
| SCHEMBL28693642 | 0.77 | CHEK1 (0.49) | PARP1KDM4CROCK2PRKACAPRKCD | |
| SCHEMBL1934489 | 0.76 | AURKA (0.46) | GSK3BJAK2AURKADAPK3ROCK2 | |
| SCHEMBL21224465 | 0.75 | PARP1 (0.52) | PARP1KDM4CKDM4AKDM4BKDM5C | |
| SCHEMBL3394071 | 0.72 | PARP1 (0.60) | PARP1KDM4CKDM4AKDM4BKDM5C | |
| SCHEMBL13859948 | 0.72 | IMPDH2 (0.50) | PARP1KDM4CKDM4AKDM4BKDM5C | |
| SCHEMBL4565869 | 0.71 | PARP1 (0.41) | PARP1KDM4CKDM4AKDM4BKDM5C | |
| SCHEMBL11898184 | 0.71 | JAK2 (0.50) | PARP1KDM4CKDM4AKDM4BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377671-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-09 | — | — | CN | disclosed |