Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.58 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.51 |
| ▸ | ROS1 | P08922 | 2/20 | 0.51 |
| ▸ | INSR | P06213 | 1/20 | 0.51 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26906712 | 1.00 | EGFR (0.58) | EGFRALKROS1INSRIGF1R | |
| SCHEMBL29904655 | 0.91 | EGFR (0.52) | EGFRALKROS1INSRIGF1R | |
| SCHEMBL26906835 | 0.91 | EGFR (0.52) | EGFRALKROS1INSRIGF1R | |
| SCHEMBL26906955 | 0.85 | EGFR (0.61) | EGFRALKINSRIGF1R | |
| SCHEMBL29904670 | 0.84 | EGFR (0.51) | EGFRALKROS1FLT3 | |
| SCHEMBL26906518 | 0.84 | EGFR (0.51) | EGFRALKROS1FLT3 | |
| SCHEMBL26906770 | 0.83 | EGFR (0.49) | EGFR | |
| SCHEMBL29904622 | 0.82 | EGFR (0.70) | EGFRALKROS1INSRIGF1R | |
| SCHEMBL29114866 | 0.82 | EGFR (0.70) | EGFRALKROS1INSRIGF1R | |
| SCHEMBL26906573 | 0.79 | EGFR (0.61) | EGFRALKINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4286376-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | Therapex Co., Ltd. (KR) | 2023-12-06 | — | — | EP | claimed |