Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.70 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.63 |
| ▸ | ROS1 | P08922 | 3/20 | 0.63 |
| ▸ | INSR | P06213 | 2/20 | 0.58 |
| ▸ | IGF1R | P08069 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29114866 | 1.00 | EGFR (0.70) | EGFRALKROS1INSRIGF1R | |
| SCHEMBL26906730 | 0.88 | ALK (0.60) | EGFRALKROS1INSRIGF1R | |
| SCHEMBL29904684 | 0.88 | ALK (0.60) | EGFRALKROS1INSRIGF1R | |
| SCHEMBL26906554 | 0.86 | EGFR (0.68) | EGFRALKINSRIGF1R | |
| SCHEMBL29114873 | 0.83 | ALK (0.74) | EGFRALKROS1INSRIGF1R | |
| SCHEMBL26906653 | 0.83 | ALK (0.69) | EGFRALKROS1INSRIGF1R | |
| SCHEMBL30692634 | 0.82 | EGFR (0.58) | EGFRALKROS1INSRIGF1R | |
| SCHEMBL26906712 | 0.82 | EGFR (0.58) | EGFRALKROS1INSRIGF1R | |
| SCHEMBL21846986 | 0.82 | EGFR (1.00) | EGFRALKROS1INSRIGF1R | |
| SCHEMBL26906637 | 0.82 | EGFR (0.82) | EGFRALKINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022211573-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2022-10-06 | — | — | WO | claimed |
| WO-2022211573-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2022-10-06 | — | — | WO | disclosed |