Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24244951 | 1.00 | PDE4B (0.46) | PDE4BKMT2AUSP30GPR119ALDH1A1 | |
| SCHEMBL22551223 | 1.00 | PDE4B (0.46) | PDE4BKMT2AUSP30GPR119ALDH1A1 | |
| SCHEMBL31549592 | 0.93 | KMT2A (0.48) | PDE4BKMT2AGPR119ALDH1A1TP53 | |
| SCHEMBL30988622 | 0.91 | PDE4B (0.46) | PDE4BKMT2AUSP30GPR119ALDH1A1 | |
| SCHEMBL30988638 | 0.91 | PDE4B (0.46) | PDE4BKMT2AUSP30GPR119ALDH1A1 | |
| SCHEMBL31549608 | 0.91 | PDE4B (0.46) | PDE4BKMT2AUSP30GPR119ALDH1A1 | |
| SCHEMBL24244962 | 0.87 | USP30 (0.47) | PDE4BKMT2AUSP30GPR119ALDH1A1 | |
| SCHEMBL15961873 | 0.87 | USP30 (0.47) | PDE4BKMT2AUSP30GPR119ALDH1A1 | |
| SCHEMBL24244961 | 0.87 | USP30 (0.47) | PDE4BKMT2AUSP30GPR119ALDH1A1 | |
| SCHEMBL8194766 | 0.87 | ALDH1A1 (0.57) | PDE4BKMT2AGPR119ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001893-A1 | SMALL MOLECULE MODULATORS OF STAT6 | GILEAD SCIENCES INC (US) | 2026-01-01 | — | — | US | disclosed |
| US-20250340551-A1 | SMALL MOLECULE MODULATORS OF STAT6 | GILEAD SCIENCES INC (US) | 2025-11-06 | — | — | US | disclosed |
| US-20250325677-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-23 | — | — | US | disclosed |
| US-20250320205-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-16 | — | — | US | disclosed |
| US-20250320206-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-16 | — | — | US | disclosed |
| EP-2960238-B1 | MONOCYCLIC PYRIDINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2017-04-05 | — | — | EP | disclosed |
| EP-2960238-A1 | MONOCYCLIC PYRIDINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2015-12-30 | — | — | EP | disclosed |
| US-8933099-B2 | Monocyclic pyridine derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-01-13 | — | — | US | disclosed |
| US-8933099-B2 | Monocyclic pyridine derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-01-13 | — | — | US | disclosed |
| US-20140235614-A1 | MONOCYCLIC PYRIDINE DERIVATIVE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2014-08-21 | — | — | US | disclosed |
| US-20140235614-A1 | MONOCYCLIC PYRIDINE DERIVATIVE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2014-08-21 | — | — | US | disclosed |
| US-7842688-B2 | Organic compounds | NOVARTIS PHARMA AG (CH) | 2010-11-30 | — | — | US | disclosed |
| US-7790715-B2 | Organic compounds | NOVARTIS AG (CH) | 2010-09-07 | — | — | US | disclosed |
| US-20090012055-A1 | Organic compounds | HEROLD PETER | 2009-01-08 | — | — | US | disclosed |
| EP-1961752-A2 | Piperidine Compounds | Speedel Experimenta AG (CH) | 2008-08-27 | — | — | EP | disclosed |
| US-20070010511-A1 | Organic compounds | NOVARTIS PHARMA AG (CH) | 2007-01-11 | — | — | US | disclosed |
| EP-1670760-A1 | ORGANIC COMPOUNDS | Speedel Experimenta AG (CH) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005061457-A1 | ORGANIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2005-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012055-A1 | Organic compounds | REN, ACE, ACE2 | PDE4B 312/4885KMT2A 3839/4885USP30 3872/4885 |
| US-20070010511-A1 | Organic compounds | REN, ACE, ACE2 | PDE4B 312/4885KMT2A 3839/4885USP30 3872/4885 |
| US-20250325677-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | PDE4B 985/4885KMT2A 440/4885USP30 1139/4885 |
| US-20250340551-A1 | SMALL MOLECULE MODULATORS OF STAT6 | STAT6, STAT1, STAT5B | PDE4B 588/4885KMT2A 684/4885USP30 2781/4885 |
| US-20140235614-A1 | MONOCYCLIC PYRIDINE DERIVATIVE | FGFR2, FGFR1, FGFR3 | PDE4B 1813/4885KMT2A 1269/4885USP30 4797/4885 |
| US-20260001893-A1 | SMALL MOLECULE MODULATORS OF STAT6 | STAT6, NCOR1, NCOR2 | PDE4B 1635/4885KMT2A 1551/4885USP30 3903/4885 |
| US-20250320205-A1 | STAT6 DEGRADERS | STAT6, STAT1, STAT5B | PDE4B 1119/4885KMT2A 396/4885USP30 1157/4885 |
| US-20250320206-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | PDE4B 985/4885KMT2A 440/4885USP30 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.