Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.65 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.65 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16245269 | 0.86 | PDCD1 (0.76) | CD274PDCD1PDK2 | |
| SCHEMBL3858523 | 0.82 | KCNN4 (0.51) | CD274PDCD1KCNN4PDK2ALDH1A1 | |
| SCHEMBL3127809 | 0.82 | PDCD1 (0.53) | CD274PDCD1KCNN4ALDH1A1ACHE | |
| SCHEMBL6027619 | 0.81 | PDCD1 (0.69) | CD274PDCD1PDK2VSIRMAPT | |
| SCHEMBL30255315 | 0.81 | PDCD1 (0.69) | CD274PDCD1PDK2VSIRMAPT | |
| SCHEMBL358303 | 0.79 | CD274 (1.00) | CD274PDCD1ALDH1A1 | |
| SCHEMBL6029512 | 0.79 | PDCD1 (0.66) | CD274PDCD1ALDH1A1MAPTCA9 | |
| SCHEMBL29558512 | 0.79 | CD274 (1.00) | CD274PDCD1ALDH1A1 | |
| SCHEMBL31396692 | 0.78 | CD274 (0.65) | CD274PDCD1CA12CA9LMNA | |
| SCHEMBL22401073 | 0.78 | PDCD1 (0.70) | CD274PDCD1DHODHGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119768390-A | Novel bicyclo PD-L1 inhibitor and preparation method and medical application thereof | 西安新通药物研究股份有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-116854667-A | Proteolytic targeted chimera for targeted degradation of PD-L1 and application thereof | 浙江工业大学 | 2023-10-10 | — | — | CN | disclosed |