SCHEMBL358303

SCHEMBL358303

Cc1c(CO)cccc1-c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 12/20 1.00
PDCD1 Q15116 3/20 1.00
EPHX1 P07099 2/20 0.48
DPP4 P27487 1/20 0.47
PTGS1 P23219 1/20 0.46
KMT2A Q03164 1/20 0.44
FOLH1 Q04609 1/20 0.42
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
BCL2L1 Q07817 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29558512 1.00 CD274 (1.00) CD274PDCD1EPHX1DPP4PTGS1
SCHEMBL16245269 0.87 PDCD1 (0.76) CD274PDCD1EPHX1PTGS1KMT2A
SCHEMBL607544 0.83 CD274 (0.71) CD274PDCD1EPHX1DPP4PTGS1
SCHEMBL30828918 0.82 PDCD1 (0.70) CD274PDCD1EPHX1PTGS1
SCHEMBL22401073 0.82 PDCD1 (0.70) CD274PDCD1EPHX1PTGS1
SCHEMBL18367730 0.82 CD274 (0.70) CD274PDCD1EPHX1KMT2AHSD17B10
SCHEMBL30091380 0.82 PDCD1 (0.69) CD274PDCD1EPHX1ALDH1A1
SCHEMBL11074941 0.82 PDCD1 (0.69) CD274PDCD1EPHX1ALDH1A1
SCHEMBL7107915 0.82 CD274 (0.69) CD274PDCD1EPHX1DPP4PTGS1
SCHEMBL21153739 0.82 CD274 (0.69) CD274PDCD1EPHX1DPP4PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 531 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119569567-A Preparation method of bifenthrin 山东智荟检测科技有限公司 2025-03-07 CN claimed
CN-118702774-A Preparation method and application of polypeptide coupling compound of targeted GPC-3 protein 上海大学 2024-09-27 CN claimed
CN-115181120-B Preparation method of 2-methyl-3-phenylstyryl pinacol borate 山东百启生物医药有限公司 2024-05-28 CN claimed
CN-115043784-B Biphenyl-1, 2, 3-triazole conjugate and preparation method and application thereof 浙江工业大学 2024-04-26 CN claimed
CN-117683021-A PD-1/PD-L1 pathway targeting compound and nuclide marker, preparation and application thereof 厦门大学 2024-03-12 CN claimed
CN-116947779-A Cyclic micromolecule compound and preparation method and application thereof 南方医科大学 2023-10-27 CN claimed
CN-115181120-A Preparation method of 2-methyl-3-phenyl styryl pinacol borate 山东百启生物医药有限公司 2022-10-14 CN claimed
CN-115043784-A Biphenyl-1, 2, 3-triazole conjugate and preparation method and application thereof 浙江工业大学 2022-09-13 CN claimed
CN-114573563-A Bifunctional molecular compound for inducing PD-L1 protein degradation and preparation and application thereof 沈阳药科大学 2022-06-03 CN claimed
CN-108218696-B Production process of bifenthrin 江苏优嘉植物保护有限公司 2021-03-26 CN claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
US-6875885-B2 Process for the preparation of enantiomerically pure pyrethroid insecticides SYNGENTA LIMITED (GB) 2005-04-05 US claimed
US-20030199709-A1 Process for the preparation of enantiomerically pure pyrethroid insecticides SYNGENTA LIMITED (GB) 2003-10-23 US claimed
CN-1443153-A Process for preparation of enantiomerically pure pyrethroid insecticides SYNGENTA LTD (GB) 2003-09-17 CN claimed
WO-2003053905-A1 A PROCESS FOR THE PRODUCTION OF 1R PYRETHROID ESTERS SYNGENTA LIMITED (GB) 2003-07-03 WO claimed
EP-1303474-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE PYRETHROID INSECTICIDES Syngenta Limited (GB) 2003-04-23 EP claimed
WO-2002006202-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE PYRETHROID INSECTICIDES SYNGENTA LIMITED (GB) 2002-01-24 WO claimed
EP-0063374-B1 SUBSTITUTED BIPHENYL COMPOUNDS FMC Corporation (US) 1984-02-22 EP claimed
EP-0063374-A1 Substituted biphenyl compounds FMC Corporation (US) 1982-10-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199709-A1 Process for the preparation of enantiomerically pure pyrethroid insecticides CYP4B1, CYP4A11, DDT CD274 4787/4885PDCD1 4337/4885EPHX1 212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.