Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585924 | 0.92 | NPY1R (0.49) | NPY1RNPY2RPTGDR2 | |
| SCHEMBL24329333 | 0.84 | NPY1R (0.43) | NPY1RNPY2RSLC6A4HTR6 | |
| SCHEMBL24329571 | 0.83 | NPY1R (0.46) | NPY1RNPY2RSLC6A4HTR6 | |
| SCHEMBL25369504 | 0.80 | NPY1R (0.57) | NPY1RNPY2RPTGDR2SLC6A4HTR6 | |
| SCHEMBL25371685 | 0.80 | NPY1R (0.60) | NPY1RNPY2RPTGDR2 | |
| SCHEMBL30694792 | 0.80 | NPY1R (0.60) | NPY1RNPY2RPTGDR2 | |
| SCHEMBL29333365 | 0.78 | PTGDR2 (0.37) | PTGDR2SLC6A4 | |
| SCHEMBL29333369 | 0.78 | PTGDR2 (0.37) | PTGDR2SLC6A4 | |
| SCHEMBL20562112 | 0.77 | NPY1R (0.42) | NPY1RNPY2R | |
| SCHEMBL128318 | 0.77 | ALOX15 (0.46) | NPY1RNPY2RSLC6A4HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4648851-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | Astrazeneca AB (SE) | 2025-11-19 | — | — | EP | disclosed |
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |
| WO-2024149728-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | ASTRAZENECA AB (SE) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024149728-A1 | SUBSTITUTED (HETERO)ANILINES AND THEIR USE | ASTRAZENECA AB (SE) | 2024-07-18 | — | — | WO | disclosed |