Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 10/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29215354 | 0.82 | MAPT (0.47) | LMNAALDH1A1 | |
| SCHEMBL31474259 | 0.81 | HDAC3 (0.53) | HDAC3HDAC2HDAC6LMNATHRB | |
| Hydrochloric Acid SCHEMBL29215321 | 0.80 | HDAC3 (0.52) | HDAC3HDAC2HDAC6LMNATHRB | |
| SCHEMBL23306608 | 0.77 | RECQL (0.40) | HDAC3HDAC2HDAC4HDAC1HDAC7 | |
| SCHEMBL21066378 | 0.76 | DPP4 (0.38) | HDAC3HDAC2HDAC4HDAC1HDAC7 | |
| SCHEMBL26613680 | 0.70 | PARP1 (0.49) | HDAC3HDAC2KCNH2 | |
| SCHEMBL18282487 | 0.70 | ALDH1A1 (0.35) | SCDALDH1A1 | |
| SCHEMBL20163031 | 0.69 | CKS1B (0.50) | LMNAALDH1A1 | |
| SCHEMBL5041530 | 0.66 | SMN1; SMN2 (0.45) | LMNATHRBDPP4OGARAB9A | |
| SCHEMBL20771270 | 0.66 | TDP1 (0.65) | HDAC3HDAC2HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023232069-A1 | AZAQUINOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 成都苑东生物制药股份有限公司 | 2023-12-07 | — | — | WO | disclosed |