Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 8/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29215321 | 0.99 | HDAC3 (0.52) | HDAC3HDAC2KCNH2MAPK8MAPK9 | |
| SCHEMBL30695510 | 0.81 | HDAC3 (0.40) | HDAC3HDAC2KCNH2LMNATHRB | |
| SCHEMBL23560975 | 0.76 | HDAC6 (0.55) | HDAC3HDAC2MAPK8MAPK9MAPK10 | |
| SCHEMBL31474329 | 0.75 | HDAC2 (0.56) | HDAC3HDAC2KCNH2HDAC6 | |
| Hydrochloric Acid SCHEMBL29215320 | 0.74 | HDAC2 (0.54) | HDAC3HDAC2KCNH2HDAC6 | |
| SCHEMBL30898853 | 0.74 | TPSAB1 (0.34) | HDAC3HDAC2KCNH2MAPK8MAPK9 | |
| SCHEMBL27122851 | 0.73 | PARP1 (0.47) | HDAC3HDAC2KCNH2MAPK8MAPK9 | |
| SCHEMBL29115584 | 0.71 | HDAC3 (0.54) | HDAC3HDAC2KCNH2HDAC6 | |
| SCHEMBL30542912 | 0.71 | HDAC3 (0.54) | HDAC3HDAC2KCNH2HDAC6 | |
| SCHEMBL20181688 | 0.70 | HDAC3 (1.00) | HDAC3HDAC2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346573-A1 | AZAQUINOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | CHENGDU EASTON BIOPHARMACEUTICALS CO LTD (CN) | 2025-11-13 | — | — | US | disclosed |
| EP-4534533-A1 | AZAQUINOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Chengdu Easton Biopharmaceuticals Co., Ltd. (CN) | 2025-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346573-A1 | AZAQUINOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | PARP1, PARP8, PARP11 | HDAC3 1400/4885HDAC2 482/4885KCNH2 4555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.