Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.57 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.55 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.55 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.55 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.55 |
| ▸ | RAF1 | P04049 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093458 | 1.00 | HDAC8 (0.62) | HDAC8HDAC6HDAC3KCNK9P2RX1 | |
| SCHEMBL23213561 | 0.87 | MEN1 (0.50) | HDAC8HDAC6HDAC3KCNK9MEN1 | |
| SCHEMBL32675964 | 0.87 | RAF1 (0.65) | HDAC8HDAC6HDAC3KCNK9P2RX1 | |
| SCHEMBL28923619 | 0.86 | MEN1 (0.49) | HDAC8HDAC6HDAC3KCNK9MEN1 | |
| SCHEMBL17925886 | 0.86 | MEN1 (0.57) | MEN1KMT2AMAPTHTTRAB9A | |
| SCHEMBL7541399 | 0.86 | MEN1 (0.49) | HDAC8HDAC6HDAC3KCNK9P2RX1 | |
| SCHEMBL18233002 | 0.86 | KMT2A (0.71) | HDAC8HDAC6HDAC3KCNK9KCNJ6 | |
| SCHEMBL2093456 | 0.85 | HDAC8 (0.62) | HDAC8HDAC6HDAC3KCNK9P2RX1 | |
| SCHEMBL1689404 | 0.85 | HDAC3 (0.62) | HDAC8HDAC6HDAC3KCNK9P2RX1 | |
| Ammonia Solution, Strong SCHEMBL28873301 | 0.84 | MAPT (0.55) | MEN1KMT2AMAPTHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |