SCHEMBL7541399

SCHEMBL7541399

CC(C)(Cl)c1cccc(NC(=O)O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
MAPT P10636 2/20 0.49
HTT P42858 1/20 0.49
RAB9A P51151 1/20 0.49
HDAC3 O15379 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
KCNK9 Q9NPC2 1/20 0.46
TP53 P04637 1/20 0.46
P2RX1 P51575 1/20 0.46
KCNJ6 P48051 1/20 0.46
KCNJ5 P48544 1/20 0.46
KCNJ3 P48549 1/20 0.46
ALDH1A1 P00352 4/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
CYP1A2 P05177 1/20 0.45
POLB P06746 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2093458 0.86 HDAC8 (0.62) MEN1KMT2AMAPTHTTRAB9A
SCHEMBL30695893 0.86 HDAC8 (0.62) MEN1KMT2AMAPTHTTRAB9A
SCHEMBL23213561 0.84 MEN1 (0.50) MEN1KMT2AMAPTHTTRAB9A
SCHEMBL28923619 0.83 MEN1 (0.49) MEN1KMT2AMAPTHTTRAB9A
SCHEMBL17925886 0.83 MEN1 (0.57) MEN1KMT2AMAPTHTTRAB9A
Ammonia Solution, Strong SCHEMBL28873301 0.81 MAPT (0.55) MEN1KMT2AMAPTHTTRAB9A
SCHEMBL4246150 0.79 BRAF (0.50) MEN1KMT2AMAPTHTTRAB9A
SCHEMBL30130682 0.79 MAPT (0.75) MEN1KMT2AMAPTHTTRAB9A
SCHEMBL2096025 0.79 MAPT (0.75) MEN1KMT2AMAPTHTTRAB9A
SCHEMBL11858223 0.77 GPR35 (0.67) MEN1KMT2AMAPTKCNK9TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1200614-A1 HERBICIDE RESISTANT TRANSGENIC PLANTS WITH MUTATED ALPHA-TUBULIN Albert-Ludwigs-Universität Freiburg (DE) 2002-05-02 EP claimed
WO-2001009354-A1 HERBICIDE RESISTANT TRANSGENIC PLANTS WITH MUTATED ALPHA-TUBULIN ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2001-02-08 WO claimed
EP-1200614-A1 HERBICIDE RESISTANT TRANSGENIC PLANTS WITH MUTATED ALPHA-TUBULIN Albert-Ludwigs-Universität Freiburg (DE) 2002-05-02 EP disclosed
WO-2001009354-A1 HERBICIDE RESISTANT TRANSGENIC PLANTS WITH MUTATED ALPHA-TUBULIN ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2001-02-08 WO disclosed