SCHEMBL30697108

SCHEMBL30697108

CCCCOc1cscc1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 5/20 0.43
S1PR3 Q99500 1/20 0.43
TP53 P04637 2/20 0.43
TSHR P16473 1/20 0.42
PLA2G4B P0C869 2/20 0.41
PTPN1 P18031 1/20 0.41
PTPN6 P29350 1/20 0.41
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11468242 0.84 TSHR (0.51) TP53TSHRPTPN1KDM4EALDH1A1
SCHEMBL14670152 0.83 THRB (0.42) TSHRALDH1A1
SCHEMBL740412 0.79 CYP1A2 (0.47) SMN1; SMN2
SCHEMBL11750259 0.79 MEN1 (0.43) PTPN11S1PR3TP53TSHRPTPN1
SCHEMBL11721778 0.78 LMNA (0.46) PTPN11S1PR3TP53TSHRALDH1A1
SCHEMBL8167721 0.77 PTPN11 (0.61) PTPN11S1PR3TP53TSHRPLA2G4B
SCHEMBL21359793 0.75 CYP1A2 (0.44) TP53KDM4EALDH1A1SMN1; SMN2
SCHEMBL27847176 0.75 CYP1A2 (0.44) TP53KDM4EALDH1A1SMN1; SMN2
Ethylene SCHEMBL29270268 0.75 CYP1A2 (0.44) SMN1; SMN2
Hydrochloric Acid SCHEMBL9038246 0.75 PTPN11 (0.60) PTPN11S1PR3TP53TSHRPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111655685-B Thiophene derivative and use thereof 藤本株式会社 2023-11-17 CN disclosed