Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 3/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | TGM1 | P22735 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26919173 | 0.91 | AXL (0.43) | MERTKCDK2CDK1CCNB1CCNE1 | |
| SCHEMBL26919164 | 0.91 | AXL (0.43) | MERTKCDK2CDK1CCNB1CCNE1 | |
| SCHEMBL29763036 | 0.91 | AXL (0.43) | MERTKCDK2CDK1CCNB1CCNE1 | |
| SCHEMBL26944092 | 0.89 | IKBKB (0.47) | MERTKCDK2CDK1CCNB1CCNE1 | |
| SCHEMBL30496642 | 0.88 | MERTK (0.41) | MERTKCDK2CDK1CCNB1CCNE1 | |
| SCHEMBL30697139 | 0.87 | IDH1 (0.44) | ALKCDK2CDK1CCNB1CCNE1 | |
| SCHEMBL26943178 | 0.87 | CDK2 (0.44) | MERTKCDK2CDK1CCNB1CCNE1 | |
| SCHEMBL26943177 | 0.87 | CDK2 (0.43) | MERTKCDK2CDK1CCNB1CCNE1 | |
| SCHEMBL26943302 | 0.86 | IKBKB (0.45) | MERTKCDK2CDK1CCNB1CCNE1 | |
| SCHEMBL26943284 | 0.86 | CDK2 (0.41) | MERTKCDK2CDK1CCNB1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250009745-A1 | CDK INHIBITOR | SHANGHAI QILU PHARMACEUTICAL RESEARCH AND DEVELOPMENT CENTRE LTD. (CN) | 2025-01-09 | — | — | US | disclosed |
| EP-4289835-A1 | CDK INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250009745-A1 | CDK INHIBITOR | CDK9, CDKL1, CDK6 | MERTK 3148/4885ALK 3371/4885CDK2 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.