Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22711363 | 1.00 | NCF1 (0.48) | NCF1HTTRECQLKDM4EALDH1A1 | |
| SCHEMBL23039621 | 0.89 | CCR5 (0.46) | HTTRECQLALDH1A1HPGDHRH3 | |
| SCHEMBL22711458 | 0.85 | HTT (0.45) | NCF1HTTRECQLKDM4EALDH1A1 | |
| SCHEMBL30696977 | 0.85 | HTT (0.45) | NCF1HTTRECQLKDM4EALDH1A1 | |
| SCHEMBL30697012 | 0.83 | NCF1 (0.51) | NCF1HTTRECQLKDM4EALDH1A1 | |
| SCHEMBL23039631 | 0.83 | NCF1 (0.51) | NCF1HTTRECQLKDM4EALDH1A1 | |
| SCHEMBL30697121 | 0.82 | CYP2A13 (0.46) | HTTRECQLKDM4EALDH1A1PDCD1 | |
| SCHEMBL23039625 | 0.82 | CYP2A13 (0.46) | HTTRECQLKDM4EALDH1A1PDCD1 | |
| SCHEMBL22711422 | 0.80 | HTT (0.46) | HTTHRH3CCR5 | |
| SCHEMBL22711452 | 0.77 | HRH3 (0.51) | HRH3CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655685-B | Thiophene derivative and use thereof | 藤本株式会社 | 2023-11-17 | — | — | CN | disclosed |