Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27081690 | 1.00 | CDK9 (0.43) | CDK9HDAC1HDAC6HSD11B1TYMS | |
| SCHEMBL29967753 | 0.79 | PRMT5 (0.42) | HDAC6ALDH1A1ALOX15 | |
| SCHEMBL27083011 | 0.79 | PRMT5 (0.42) | HDAC6ALDH1A1ALOX15 | |
| SCHEMBL29967680 | 0.78 | MAPT (0.45) | HDAC6KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL27081782 | 0.78 | MAPT (0.45) | HDAC6KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL23754421 | 0.78 | ACHE (0.57) | HDAC1HDAC6ALDH1A1HSD17B10MEN1 | |
| SCHEMBL30027318 | 0.78 | ACHE (0.57) | HDAC1HDAC6ALDH1A1HSD17B10MEN1 | |
| SCHEMBL27083027 | 0.77 | MAPT (0.44) | HDAC1HDAC6KMT2A | |
| SCHEMBL29967557 | 0.77 | MAPT (0.44) | HDAC1HDAC6KMT2A | |
| SCHEMBL12359624 | 0.76 | XIAP (0.44) | CDK9HDAC1HDAC6XIAPBIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062812-A | Indoline derivatives as DDR inhibitors | 奇斯药制品公司 | 2023-11-14 | — | — | CN | disclosed |