Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 7/20 | 0.38 |
| ▸ | RXRB | P28702 | 4/20 | 0.38 |
| ▸ | RXRG | P48443 | 4/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 2/20 | 0.38 |
| ▸ | SULT1E1 | P49888 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19770987 | 0.81 | ESR1 (0.46) | ESR1ESR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL5013007 | 0.81 | ESR1 (0.46) | ESR1ESR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL5013008 | 0.81 | ESR1 (0.46) | ESR1ESR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL29403700 | 0.79 | ESR1 (0.48) | ESR1ESR2TSHRALDH1A1CYP3A4 | |
| Sugiol SCHEMBL28605319 | 0.73 | SOD1 (0.58) | ESR1ESR2ALDH1A1CYP3A4MAPT | |
| Sugiol SCHEMBL17407685 | 0.73 | SOD1 (0.58) | ESR1ESR2ALDH1A1CYP3A4MAPT | |
| Sugiol SCHEMBL1086916 | 0.73 | SOD1 (0.58) | ESR1ESR2ALDH1A1CYP3A4MAPT | |
| SCHEMBL3706021 | 0.70 | CYP3A4 (0.69) | ESR1ESR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL19786216 | 0.67 | ESR1 (0.42) | ESR1ESR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL14880592 | 0.65 | TSHR (0.56) | ESR1ESR2TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117064951-A | A Chinese medicinal composition for treating hemorrhoid, and its preparation method | 成都医学院 | 2023-11-17 | — | — | CN | disclosed |