Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | SULT1E1 | P49888 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 3/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13856769 | 0.73 | TSHR (1.00) | TSHRSULT1E1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL8667490 | 0.73 | TSHR (0.59) | TSHRSULT1E1CYP19A1ALDH1A1FDPS | |
| SCHEMBL16010771 | 0.70 | TSHR (0.35) | TSHRSULT1E1CYP19A1 | |
| SCHEMBL13446722 | 0.69 | SULT1E1 (1.00) | TSHRSULT1E1ALDH1A1CYP3A4MAPT | |
| SCHEMBL5013007 | 0.67 | ESR1 (0.46) | TSHRSULT1E1CYP19A1ALDH1A1CYP3A4 | |
| SCHEMBL19770987 | 0.67 | ESR1 (0.46) | TSHRSULT1E1CYP19A1ALDH1A1CYP3A4 | |
| SCHEMBL5013008 | 0.67 | ESR1 (0.46) | TSHRSULT1E1CYP19A1ALDH1A1CYP3A4 | |
| SCHEMBL29403700 | 0.67 | ESR1 (0.48) | TSHRSULT1E1CYP19A1ALDH1A1CYP3A4 | |
| SCHEMBL30697299 | 0.65 | ESR1 (0.46) | TSHRSULT1E1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL14880005 | 0.64 | CYP19A1 (0.49) | TSHRCYP19A1ALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150059018-A1 | METHODS AND COMPOSITIONS FOR PRODUCING DRIMENOL | KEYGENE N.V. (NL) | 2015-02-26 | — | — | US | claimed |
| EP-2768955-A1 | METHODS AND COMPOSITIONS FOR PRODUCING DRIMENOL | Keygene N.V. (NL) | 2014-08-27 | — | — | EP | claimed |
| WO-2013058655-A1 | METHODS AND COMPOSITIONS FOR PRODUCING DRIMENOL | KEYGENE N.V. (NL) | 2013-04-25 | — | — | WO | claimed |
| US-20150059018-A1 | METHODS AND COMPOSITIONS FOR PRODUCING DRIMENOL | KEYGENE N.V. (NL) | 2015-02-26 | — | — | US | disclosed |
| US-20140259223-A1 | METHODS FOR PRODUCING CINNAMOLIDE AND/OR DRIMENDIOL | KEYGENE N.V. (NL) | 2014-09-11 | — | — | US | disclosed |
| EP-2768955-A1 | METHODS AND COMPOSITIONS FOR PRODUCING DRIMENOL | Keygene N.V. (NL) | 2014-08-27 | — | — | EP | disclosed |
| EP-2768952-A2 | METHODS FOR PRODUCING CINNAMOLIDE AND/OR DRIMENDIOL | Keygene N.V. (NL) | 2014-08-27 | — | — | EP | disclosed |
| WO-2013058654-A2 | METHODS FOR PRODUCING CINNAMOLIDE AND/OR DRIMENDIOL | KEYGENE N.V. (NL) | 2013-04-25 | — | — | WO | disclosed |
| WO-2013058655-A1 | METHODS AND COMPOSITIONS FOR PRODUCING DRIMENOL | KEYGENE N.V. (NL) | 2013-04-25 | — | — | WO | disclosed |