SCHEMBL30697339

SCHEMBL30697339

CO[C@@]1(n2cnc3c(=O)[nH]c(N)nc32)O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.53
FUT5 Q11128 1/20 0.52
POLG P54098 2/20 0.51
KRAS P01116 2/20 0.51
PNP P00491 1/20 0.50
P2RY6 Q15077 2/20 0.49
P2RY2 P41231 1/20 0.49
P2RY4 P51582 1/20 0.49
NT5E P21589 1/20 0.49
POLB P06746 2/20 0.48
P2RX3 P56373 3/20 0.46
DCPS Q96C86 1/20 0.46
ENPP1 P22413 2/20 0.45
P2RY1 P47900 2/20 0.45
P2RX1 P51575 2/20 0.45
P2RY11 Q96G91 1/20 0.45
P2RX4 Q99571 1/20 0.45
POLA1 P09884 1/20 0.45
IMPDH2 P12268 1/20 0.44
IMPDH1 P20839 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30603197 0.99 TGM2 (0.54) TGM2FUT5POLGKRASPNP
SCHEMBL29093615 0.92 NT5E (0.52) TGM2FUT5KRASPNPP2RY6
SCHEMBL28993982 0.91 POLG (0.51) TGM2FUT5POLGKRASPNP
SCHEMBL4076696 0.88 POLG (0.53) TGM2FUT5POLGKRASPNP
SCHEMBL309062 0.87 TGM2 (0.53) TGM2FUT5POLGKRASPNP
SCHEMBL4410921 0.87 TGM2 (0.55) TGM2FUT5POLGKRASPNP
SCHEMBL8435629 0.87 POLG (0.51) TGM2FUT5POLGKRASPNP
SCHEMBL4381958 0.87 POLG (0.53) TGM2FUT5POLGKRASPNP
SCHEMBL8438356 0.86 POLG (0.53) TGM2FUT5POLGKRASPNP
SCHEMBL401417 0.86 TGM2 (0.53) TGM2FUT5POLGKRASPNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117247932-A Method for improving utilization rate of cap analogues in-vitro transcription 南京诺唯赞生物科技股份有限公司 2023-12-19 CN disclosed